FAP Antikörper (C-Term)

Produktnummer ABIN2782638

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FAP in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Meerschweinchen und Kaninchen.

Kurzübersicht für FAP Antikörper (C-Term) (ABIN2782638)

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FAP Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: FAP Antibody - C-terminal region

Sequenz: SWEYYASVYT ERFMGLPTKD DNLEHYKNST VMARAEYFRN VDYLLIHGTA

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FAP. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human FAP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46455-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FAP

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Andere Bezeichnung: FAP

Hintergrund:

Background Information: The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.

Gene Name: fibroblast activation protein, alpha

Alternative Symbols: FAPA, SIMP, DPPIV, FAPalpha

Protein Name: Seprase

Molekulargewicht: 26kDa

Gen-ID: 2191

NCBI Accession: NP_004451

UniProt: Q12884

Pathways: Tube Formation