Dystrobrevin beta Antikörper (C-Term)

Produktnummer ABIN2782578

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Dystrobrevin beta in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für Dystrobrevin beta Antikörper (C-Term) (ABIN2782578)

Target: Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dystrobrevin beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Dystrobrevin beta Antikörper

Bindungsspezifität: C-Term

Sequenz: ASQPTPEKAQ QNPTLLAELR LLRQRKDELE QRMSALQESR RELMVQLEEL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DTNB. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DTNB

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 567 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Dystrobrevin beta

Target: Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))

Andere Bezeichnung: DTNB

Hintergrund: DTNB is dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin.This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: MGC17163, MGC57126
Protein Interaction Partner: CEP55, ABI3, GGA1, NUP62, MTUS2, HMG20A, ABI2, PPFIA1, VCP, TRAF2, KRT31, DTNB, DMD, ZBTB9, TXLNA, KRT40, SPZ1, DTNBP1, USHBP1, NDEL1, CEP63, MLC1, UBC, PRTFDC1, SNTG2, SNTG1, CCDC85B, TSACC, KIF5A, BEGAIN, PPFIBP2, UTRN, SNTA1, KIF5B,
Protein Size: 567

Molekulargewicht: 64 kDa

Gen-ID: 1838

NCBI Accession: NM_033148, NP_149160

UniProt: O60941