PDSS1 Antikörper (Middle Region)

Produktnummer ABIN2782535

Der Kaninchen Polyklonal anti-PDSS1 Antikörper (ABIN2782535) detektiert spezifisch PDSS1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Ratte und Pferd.

Kurzübersicht für PDSS1 Antikörper (Middle Region) (ABIN2782535)

Target: PDSS1 (Prenyl (Decaprenyl) Diphosphate Synthase, Subunit 1 (PDSS1))

Reaktivität: Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Ratte, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDSS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PDSS1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: PDSS1 Antibody - middle region

Sequenz: VIDDASSRRG KHTVNKIWGE KKAVLAGDLI LSAASIALAR IGNTTVISIL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PDSS1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PDSS1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46196-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PDSS1

Target: PDSS1 (Prenyl (Decaprenyl) Diphosphate Synthase, Subunit 1 (PDSS1))

Andere Bezeichnung: PDSS1

Hintergrund:

Targeted Subunit: 1

Background Information: PDSS1 is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. PDSS1 catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in PDSS1 gene are a cause of coenzyme Q10 deficiency.The protein encoded by this gene is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency.

Gene Name: Prenyl (decaprenyl) diphosphate synthase, subunit 1

Alternative Symbols: DPS, SPS, TPT, COQ1, TPRT, COQ1A, TPT 1, hDPS1, COQ10D2

Protein Name: Decaprenyl-diphosphate synthase subunit 1

Molekulargewicht: 46kDa

Gen-ID: 23590

NCBI Accession: NP_055132

UniProt: Q5T2R2