B-Cell Linker Antikörper (Middle Region)

Produktnummer ABIN2782531

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch B-Cell Linker in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen und Kaninchen.

Kurzübersicht für B-Cell Linker Antikörper (Middle Region) (ABIN2782531)

Target: B-Cell Linker (BLNK)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser B-Cell Linker Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-B-Cell Linker Antikörper

Bindungsspezifität: Middle Region

Sequenz: QYALGRKKNG EEYFGSVAEI IRNHQHSPLV LIDSQNNTKD STRLKYAVKV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against BLNK. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BLNK

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 456 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu B-Cell Linker

Target: B-Cell Linker (BLNK)

Andere Bezeichnung: BLNK

Hintergrund: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological function
Alias Symbols: BASH, BLNK-s, Ly57, MGC111051, SLP-65, SLP65, bca, AGM4, LY57, BLNK-S
Protein Interaction Partner: ERBB2, BTK, GRAP2, SYK, PLCG1, CBL, AIFM1, NCK2, TLN1, MAP2K4, PPP2R2C, PLCG2, MYBPC3, LYN, HSPA4, GRB2, CD79A, CAPZB, CAPZA2, CAPZA1, CLEC17A, WDR81, DOK3, SH3KBP1, CD2AP, HSPH1, VAV3, CMTM3, CBLB, CRKL, MAP4K1, LCP2, NCK1, ITK, PTPN6, VAV1, CD72,
Protein Size: 456

Molekulargewicht: 50 kDa

Gen-ID: 29760

NCBI Accession: NM_013314, NP_037446

UniProt: Q8WV28

Pathways: BCR Signaling