GLUD1 Antikörper (N-Term)

Produktnummer ABIN2782329

Dieses Anti-GLUD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GLUD1 in WB und IHC. Geeignet für Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Zebrafisch (Danio rerio), Hund, Schaf und Saccharomyces cerevisiae.

Kurzübersicht für GLUD1 Antikörper (N-Term) (ABIN2782329)

Target: GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Zebrafisch (Danio rerio), Hund, Schaf, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLUD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-GLUD1 Antikörper

Bindungsspezifität: N-Term

Sequenz: EGFFDRGASI VEDKLVEDLR TRESEEQKRN RVRGILRIIK PCNHVLSLSF

Homologie: Cow: 86%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rat: 100%, Sheep: 86%, Yeast: 86%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against GLUD1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GLUD1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 558 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GLUD1

Target: GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

Andere Bezeichnung: GLUD1

Hintergrund: L-glutamate dehydrogenase (EC 1.4.1.3) has a central role in nitrogen metabolism in plants and animals. Glutamate dehydrogenase is found in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate. Glutamate, the main substrate of GLUD, is present in brain in concentrations higher than in other organs. In nervous tissue, GLUD appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification. L-glutamate dehydrogenase (EC 1.4.1.3) has a central role in nitrogen metabolism in plants and animals. Glutamate dehydrogenase is found in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate (Smith et al., 2001 [PubMed 11254391]). Glutamate, the main substrate of GLUD, is present in brain in concentrations higher than in other organs. In nervous tissue, GLUD appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification (Mavrothalassitis et al., 1988 [PubMed 3368458]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-51 M20867.1 1-51 52-3120 BC112946.1 16-3084
Alias Symbols: GDH, GDH1, GLUD, MGC132003
Protein Interaction Partner: FUS, UBC, DCP2, KLHL29, SUMO1, NEDD8, LSM1, ILK, CDK5, VTN, SEC62, STAT5A, ORM1, HPX, NR4A1, FN1, CRP, ASGR2, CUL3, ELAVL1, EBNA-LP, HDAC5, ICT1, GLUD1, DYNLL1, GOT2,
Protein Size: 558

Molekulargewicht: 56 kDa

Gen-ID: 2746

NCBI Accession: NM_005271, NP_005262

UniProt: P00367

Pathways: Positive Regulation of Peptide Hormone Secretion, Warburg Effekt