KNG1 Antikörper (C-Term)

Produktnummer ABIN2782315

Der Kaninchen Polyklonal anti-KNG1 Antikörper (ABIN2782315) detektiert spezifisch KNG1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für KNG1 Antikörper (C-Term) (ABIN2782315)

Target: KNG1 (Kininogen 1 (KNG1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KNG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KNG1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: KNG1 Antibody - C-terminal region

Sequenz: ISLMKRPPGF SPFRSSRIGE IKEETTSHLR SCEYKGRPPK AGAEPASERE

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against KNG1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human KNG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45681-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu KNG1

Target: KNG1 (Kininogen 1 (KNG1))

Andere Bezeichnung: KNG1

Hintergrund:

Background Information: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

Gene Name: kininogen 1

Alternative Symbols: BK, BDK, KNG, HMWK

Protein Name: kininogen-1

Molekulargewicht: 32kDa

Gen-ID: 3827

NCBI Accession: NP_000884

UniProt: P01042

Pathways: ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process