KNG1 Antikörper (Middle Region)
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- Target Alle KNG1 Antikörper anzeigen
- KNG1 (Kininogen 1 (KNG1))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Schwein, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KNG1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- YPGKDFVQPP TKICVGCPRD IPTNSPELEE TLTHTITKLN AENNATFYFK
- Homologie
- Horse: 85%, Human: 100%, Mouse: 77%, Pig: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against KNG1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human KNG1
- Top Product
- Discover our top product KNG1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 644 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).
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Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).
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- Target
- KNG1 (Kininogen 1 (KNG1))
- Andere Bezeichnung
- KNG1 (KNG1 Produkte)
- Synonyme
- BDK antikoerper, BK antikoerper, KNG antikoerper, Kng antikoerper, KNG2 antikoerper, fb64g01 antikoerper, wu:fb64g01 antikoerper, zgc:103569 antikoerper, kininogen antikoerper, bdk antikoerper, kng antikoerper, KNG1 antikoerper, IHRP antikoerper, KINKG antikoerper, KINKH antikoerper, Kng1 antikoerper, Kngk antikoerper, kininogen 1 antikoerper, kininogen 1 L homeolog antikoerper, inter-alpha-trypsin inhibitor heavy chain family member 4 antikoerper, kininogen 2-like 1 antikoerper, KNG1 antikoerper, Kng1 antikoerper, kng1 antikoerper, kng1.L antikoerper, ITIH4 antikoerper, Kng2l1 antikoerper
- Hintergrund
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Kininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII and inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. The active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects such as influence in smooth muscle contraction, induction of hypotension, natriuresis and diuresis, etc.
Alias Symbols: BDK, KNG
Protein Interaction Partner: Ance, ECE1, COPS6, RXFP4, CPN1, F11, HABP2, CTSK, PREP, MEP1A, ITGB2, GP1BA, KLKB1, KNG1, VTN, THBS1, F2, PLAUR, PLG, KLK1, KRT1, FTL, ELANE, CD93, CTSL, CTSS, CTSG, CAPN2, CAPN1, AGT, APP,
Protein Size: 644 - Molekulargewicht
- 72 kDa
- Gen-ID
- 3827
- NCBI Accession
- NM_001102416, NP_001095886
- UniProt
- P01042
- Pathways
- ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
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