KNG1 Antikörper (Middle Region)

Produktnummer ABIN2782314

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-KNG1 Antikörper wird verwendet zum Nachweis von KNG1 in Proben von Human, Maus, Schwein und Pferd. Er wurde validiert für WB.

Kurzübersicht für KNG1 Antikörper (Middle Region) (ABIN2782314)

Target: KNG1 (Kininogen 1 (KNG1))

Reaktivität: Human, Maus, Schwein, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KNG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KNG1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: KNG1 Antibody - middle region

Sequenz: YPGKDFVQPP TKICVGCPRD IPTNSPELEE TLTHTITKLN AENNATFYFK

Homologie: Horse: 85%, Human: 100%, Mouse: 77%, Pig: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against KNG1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KNG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8103996

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-KNG1 Antikörper (ABIN2782314)

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Details zu KNG1

Target: KNG1 (Kininogen 1 (KNG1))

Andere Bezeichnung: KNG1

Hintergrund:

Background Information: Kininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII and inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. The active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects such as influence in smooth muscle contraction, induction of hypotension, natriuresis and diuresis, etc.

Gene Name: Kininogen 1

Alternative Symbols: BK, BDK, KNG, HMWK

Protein Name: Kininogen-1

Molekulargewicht: 72kDa

Gen-ID: 3827

NCBI Accession: NP_001095886

UniProt: P01042

Pathways: ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process