MBL2 Antikörper (Middle Region)

Produktnummer ABIN2782311

Dieser Anti-MBL2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von MBL2 in WB. Geeignet für Human, Ratte, Rind (Kuh), Ziege, Schaf, Pferd und Schwein.

Kurzübersicht für MBL2 Antikörper (Middle Region) (ABIN2782311)

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Reaktivität: Human, Ratte, Rind (Kuh), Ziege, Schaf, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MBL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MBL2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: KEEAFLGITD EKTEGQFVDL TGNRLTYTNW NEGEPNNAGS DEDCVLLLKN

Homologie: Cow: 77%, Goat: 77%, Horse: 92%, Human: 100%, Pig: 92%, Rat: 77%, Sheep: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against MBL2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MBL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 248 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MBL2

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Andere Bezeichnung: MBL2

Hintergrund: This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.
Alias Symbols: COLEC1, HSMBPC, MBL, MBP, MBP1, MGC116832, MGC116833, MBL2D, MBP-C
Protein Interaction Partner: MASP2, MAD2L1, MASP1, MBL2, PTPRC, KRT1, CD93, CALCR, CALR,
Protein Size: 248

Molekulargewicht: 24 kDa

Gen-ID: 4153

NCBI Accession: NM_000242, NP_000233

UniProt: Q66S64

Pathways: Komplementsystem, Positive Regulation of Immune Effector Process