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Retinoid X Receptor gamma Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-Retinoid X Receptor gamma-Antikörper wurde für WB validiert. Er ist geeignet, Retinoid X Receptor gamma in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Pferd, Meerschweinchen und Kaninchen zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN2782291

Kurzübersicht für Retinoid X Receptor gamma Antikörper (N-Term) (ABIN2782291)

Target

Alle Retinoid X Receptor gamma (RXRG) Antikörper anzeigen
Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Reaktivität

  • 62
  • 22
  • 19
  • 10
  • 8
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Pferd, Meerschweinchen, Kaninchen

Wirt

  • 48
  • 13
  • 1
Kaninchen

Klonalität

  • 50
  • 12
Polyklonal

Konjugat

  • 37
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Retinoid X Receptor gamma Antikörper ist unkonjugiert

Applikation

  • 32
  • 23
  • 13
  • 13
  • 9
  • 8
  • 7
  • 5
  • 5
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    NVVNSVSSSE DIKPLPGLPG IGNMNYPSTS PGSLVKHICA ICGDRSSGKH

    Homologie

    Cow: 100%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against RXRG. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human RXRG
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 463 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bungard, McGivan: "Identification of the promoter elements involved in the stimulation of ASCT2 expression by glutamine availability in HepG2 cells and the probable involvement of FXR/RXR dimers." in: Archives of biochemistry and biophysics, Vol. 443, Issue 1-2, pp. 53-9, (2005) (PubMed).

  • Target

    Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

    Andere Bezeichnung

    RXRG

    Hintergrund

    RXRG encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. RXRG is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: NR2B3, RXRC
    Protein Interaction Partner: NR1H3, NR1H2, RARB, RARA, MPPED2, UBC, CUL1, DCK, NR1H4, NCOR2, NR1I2, VDR, THRB, RARG, PPARD, MAP4, CAMK2B, CEBPZ, HOXD4, AJUBA, RPAP2, LRSAM1, PNO1, CHGB, THRA, NCOA6, PPARG, SRF, CREBBP, PPARA, NR4A1, Nr0b2, ITGB3BP,
    Protein Size: 463

    Molekulargewicht

    51 kDa

    Gen-ID

    6258

    NCBI Accession

    NM_006917, NP_008848

    UniProt

    P48443

    Pathways

    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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