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ICAM5 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ICAM5 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen und Pferd und wurde in 1 Publikation erwähnt.
Produktnummer ABIN2782226

Kurzübersicht für ICAM5 Antikörper (N-Term) (ABIN2782226)

Target

Alle ICAM5 Antikörper anzeigen
ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Reaktivität

  • 22
  • 19
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt

  • 25
  • 2
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 27
  • 3
Polyklonal

Konjugat

  • 22
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ICAM5 Antikörper ist unkonjugiert

Applikation

  • 21
  • 14
  • 9
  • 8
  • 8
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    RRNGTQRGLR WLARQLVDIR EPETQPVCFF RCARRTLQAR GLIRTFQRPD

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against ICAM5. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human ICAM5
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 924 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tian, Lappalainen, Autero, Hänninen, Rauvala, Gahmberg: "Shedded neuronal ICAM-5 suppresses T-cell activation." in: Blood, Vol. 111, Issue 7, pp. 3615-25, (2008) (PubMed).

  • Target

    ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

    Andere Bezeichnung

    ICAM5

    Hintergrund

    ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: TLCN, TLN
    Protein Interaction Partner: FBXO6, PSEN2, ITGB2, ITGAL, PSEN1,
    Protein Size: 924

    Molekulargewicht

    95 kDa

    Gen-ID

    7087

    NCBI Accession

    NM_003259, NP_003250

    UniProt

    Q9UMF0

    Pathways

    Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location
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