LTB Antikörper (N-Term)

Produktnummer ABIN2782173

Produktdetails anti-LTB Antikörper

Target: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Bindungsspezifität: N-Term

Reaktivität: Human, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LTB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AVPITVLAVL ALVPQDQGGL VTETADPGAQ AQQGLGFQKL PEEEPETDLS

Homologie: Guinea Pig: 79%, Horse: 91%, Human: 100%, Rabbit: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against LTB. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LTB

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 244 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu LTB

Target: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Andere Bezeichnung: LTB (LTB Produkte)

Synonyme: AI662801 antikoerper, LTbeta antikoerper, Tnfc antikoerper, Tnfsf3 antikoerper, p33 antikoerper, TNFC antikoerper, TNFSF3 antikoerper, LT-b antikoerper, LT-beta antikoerper, TNF-C antikoerper, lymphotoxin B antikoerper, lymphotoxin beta antikoerper, Ltb antikoerper, LTB antikoerper

Hintergrund: Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: TNFC, TNFSF3, p33
Protein Interaction Partner: TNFSF14, LTBR, LTB, TNFRSF1A, LTA,
Protein Size: 244

Molekulargewicht: 25 kDa

Gen-ID: 4050

NCBI Accession: NM_002341, NP_002332

UniProt: Q06643

Pathways: NF-kappaB Signalweg