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LTB Antikörper (Lymphotoxin beta (TNF Superfamily, Member 3)) (N-Term) Primary Antibody

LTB Reaktivität: Human, Meerschweinchen, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2782173
$389.00
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 2 bis 3 Werktagen
  • Target
    LTB
    Bindungsspezifität
    N-Term
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Reaktivität
    Human, Meerschweinchen, Pferd, Kaninchen
    • 35
    • 31
    • 18
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Wirt
    Kaninchen
    • 45
    • 3
    • 2
    Klonalität
    Polyklonal
    • 45
    • 5
    Konjugat
    Dieser LTB Antikörper ist unkonjugiert
    • 22
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Applikation
    Western Blotting (WB)
    • 30
    • 17
    • 13
    • 8
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Sequenz
    AVPITVLAVL ALVPQDQGGL VTETADPGAQ AQQGLGFQKL PEEEPETDLS
    Homologie
    Guinea Pig: 79%, Horse: 91%, Human: 100%, Rabbit: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against LTB. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human LTB
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 244 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    LTB
    Andere Bezeichnung
    LTB (LTB Antibody Abstract)
    Synonyme
    AI662801, LTbeta, Tnfc, Tnfsf3, p33, TNFC, TNFSF3, LT-b, LT-beta, TNF-C, lymphotoxin B, lymphotoxin beta, Ltb, LTB
    Hintergrund
    Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Alias Symbols: TNFC, TNFSF3, p33
    Protein Interaction Partner: TNFSF14, LTBR, LTB, TNFRSF1A, LTA,
    Protein Size: 244
    Molekulargewicht
    25 kDa
    Gen-ID
    4050
    NCBI Accession
    NM_002341, NP_002332
    UniProt
    Q06643
    Pathways
    NF-kappaB Signalweg
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