FMO4 Antikörper (N-Term)

Produktnummer ABIN2782152

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FMO4 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Hund.

Kurzübersicht für FMO4 Antikörper (N-Term) (ABIN2782152)

Target: FMO4 (Flavin Containing Monooxygenase 4 (FMO4))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FMO4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FMO4 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: FMO4 Antibody - N-terminal region

Sequenz: MVCTGHFLNP HLPLEAFPGI HKFKGQILHS QEYKIPEGFQ GKRVLVIGLG

Homologie: Cow: 100%, Dog: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FMO4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FMO4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45209-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FMO4

Target: FMO4 (Flavin Containing Monooxygenase 4 (FMO4))

Andere Bezeichnung: FMO4

Hintergrund:

Background Information: FMO4 belongs to the FMO family. Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics.

Gene Name: Flavin containing monooxygenase 4

Alternative Symbols: FMO2

Protein Name: Dimethylaniline monooxygenase [N-oxide-forming] 4

Molekulargewicht: 63kDa

Gen-ID: 2329

NCBI Accession: NP_002013

UniProt: P31512