KTN1 Antikörper (Middle Region)

Produktnummer ABIN2782098

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KTN1 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für KTN1 Antikörper (Middle Region) (ABIN2782098)

Target: KTN1 (Kinectin 1 (Kinesin Receptor) (KTN1))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KTN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KTN1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: EELLKVISER EKEISGLWNE LDSLKDAVEH QRKKNNDLRE KNWEAMEALA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against KTN1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KTN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1306 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KTN1

Target: KTN1 (Kinectin 1 (Kinesin Receptor) (KTN1))

Andere Bezeichnung: KTN1

Hintergrund: Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes. The transport of organelles requires a special class of microtubule-associated proteins (MAPs). One of these is the molecular motor kinesin, an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule. Another such MAP is kinectin, a large integral ER membrane protein. Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes. The transport of organelles requires a special class of microtubule-associated proteins (MAPs). One of these is the molecular motor kinesin (see MIM 148760 and MIM 600025), an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule. Another such MAP is kinectin, a large integral ER membrane protein. Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CG1, KIAA0004, KNT, MGC133337, MU-RMS-40.19
Protein Interaction Partner: SYNE4, CLEC7A, SGTA, MEOX2, BNIP3, UBC, MDM2, BMI1, CTPS2, EHD1, WARS, HEXA, NPM1, CDH2, NEURL4, HERC2, ARRB1, SUMO2, SUMO1, PLEKHA5, PSMD7, KIF5B, IKBKE, RAC1, RHOG, RHOA, EEF1D, CDC42, AKT1,
Protein Size: 1306

Molekulargewicht: 150 kDa

Gen-ID: 3895

NCBI Accession: NM_001079522, NP_001072990

UniProt: Q17RZ5