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CCDC90A Antikörper (Middle Region)

MCUR1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2782009
  • Target Alle CCDC90A (MCUR1) Antikörper anzeigen
    CCDC90A (MCUR1) (Mitochondrial Calcium Uniporter Regulator 1 (MCUR1))
    Bindungsspezifität
    • 15
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen
    Wirt
    • 20
    Kaninchen
    Klonalität
    • 20
    Polyklonal
    Konjugat
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCDC90A Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 5
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB)
    Sequenz
    ELHQLKQQVM DEVIKVRTDT KLDFNLEKSR VKELYSLNEK KLLELRTEIV
    Homologie
    Cow: 79%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rat: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CCDC90A. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human CCDC90A
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 359 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Shanmughapriya, Rajan, Hoffman, Zhang, Guo, Kolesar, Hines, Ragheb, Jog, Caricchio, Baba, Zhou, Kaufman, Cheung, Kurosaki, Gill, Madesh: "Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU." in: Science signaling, Vol. 8, Issue 366, pp. ra23, (2015) (PubMed).

    Mallilankaraman, Cárdenas, Doonan, Chandramoorthy, Irrinki, Golenár, Csordás, Madireddi, Yang, Müller, Miller, Kolesar, Molgó, Kaufman, Hajnóczky, Foskett, Madesh: "MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism." in: Nature cell biology, Vol. 14, Issue 12, pp. 1336-43, (2012) (PubMed).

    Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

    Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." in: Genome research, Vol. 16, Issue 1, pp. 55-65, (2006) (PubMed).

  • Target
    CCDC90A (MCUR1) (Mitochondrial Calcium Uniporter Regulator 1 (MCUR1))
    Andere Bezeichnung
    CCDC90A (MCUR1 Produkte)
    Synonyme
    C6orf79 antikoerper, CCDC90A antikoerper, 6230416A05Rik antikoerper, AU015498 antikoerper, AV136929 antikoerper, AW554392 antikoerper, C88263 antikoerper, Ccdc90a antikoerper, RGD1307673 antikoerper, mitochondrial calcium uniporter regulator 1 antikoerper, mitochondrial calcium uniporter regulator 1 L homeolog antikoerper, MCUR1 antikoerper, Mcur1 antikoerper, mcur1.L antikoerper
    Hintergrund
    Essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism.
    Alias Symbols: C6orf79, FLJ20958, CCDC90A
    Protein Size: 359
    Molekulargewicht
    40 kDa
    Gen-ID
    63933
    NCBI Accession
    NM_001031713, NP_001026883
    UniProt
    Q96AQ8
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