CCDC90A Antikörper (Middle Region)

Produktnummer ABIN2782009

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CCDC90A in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen und Pferd und wurde in 4+ Publikationen erwähnt.

Kurzübersicht für CCDC90A Antikörper (Middle Region) (ABIN2782009)

Target: CCDC90A (MCUR1) (Mitochondrial Calcium Uniporter Regulator 1 (MCUR1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC90A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CCDC90A Antikörper

Bindungsspezifität: Middle Region

Sequenz: ELHQLKQQVM DEVIKVRTDT KLDFNLEKSR VKELYSLNEK KLLELRTEIV

Homologie: Cow: 79%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CCDC90A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CCDC90A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 359 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CCDC90A Antikörper (ABIN2782009)

Shanmughapriya, Rajan, Hoffman, Zhang, Guo, Kolesar, Hines, Ragheb, Jog, Caricchio, Baba, Zhou, Kaufman, Cheung, Kurosaki, Gill, Madesh: "Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU." in: Science signaling, Vol. 8, Issue 366, pp. ra23, (2015) (PubMed).

Mallilankaraman, Cárdenas, Doonan, Chandramoorthy, Irrinki, Golenár, Csordás, Madireddi, Yang, Müller, Miller, Kolesar, Molgó, Kaufman, Hajnóczky, Foskett, Madesh: "MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism." in: Nature cell biology, Vol. 14, Issue 12, pp. 1336-43, (2012) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." in: Genome research, Vol. 16, Issue 1, pp. 55-65, (2006) (PubMed).

Details zu CCDC90A

Target: CCDC90A (MCUR1) (Mitochondrial Calcium Uniporter Regulator 1 (MCUR1))

Andere Bezeichnung: CCDC90A

Hintergrund: Essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism.
Alias Symbols: C6orf79, FLJ20958, CCDC90A
Protein Size: 359

Molekulargewicht: 40 kDa

Gen-ID: 63933

NCBI Accession: NM_001031713, NP_001026883

UniProt: Q96AQ8