Osteoactivin Antikörper (N-Term)

Produktnummer ABIN2781893

Der Kaninchen Polyklonal anti-Osteoactivin Antikörper (ABIN2781893) detektiert spezifisch Osteoactivin in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Meerschweinchen und Kaninchen.

Kurzübersicht für Osteoactivin Antikörper (N-Term) (ABIN2781893)

Target: Osteoactivin (GPNMB)

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Osteoactivin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Osteoactivin Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: GPNMB Antibody - N-terminal region

Sequenz: DENDWNEKLY PVWKRGDMRW KNSWKGGRVQ AVLTSDSPAL VGSNITFAVN

Spezifität: 100 % homologous to both isoforms of hGPNMB

Homologie: Cow: 100%, Dog: 79%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against GPNMB. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GPNMB

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8107419

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Osteoactivin

Target: Osteoactivin (GPNMB)

Andere Bezeichnung: GPNMB

Hintergrund:

Background Information: GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential.The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Glycoprotein (transmembrane) nmb

Alternative Symbols: NMB, HGFIN, PLCA3

Protein Name: cDNA FLJ78601, highly similar to Homo sapiens glycoprotein (transmembrane) nmb (GPNMB), transcript variant 2, mRNA EMBL BAF84767.1

Molekulargewicht: 63 kDa

Gen-ID: 10457

NCBI Accession: NP_002501

UniProt: Q14956