Derlin-3 Antikörper (C-Term)

Produktnummer ABIN2781869

Der Kaninchen Polyklonal anti-Derlin-3 Antikörper (ABIN2781869) detektiert spezifisch Derlin-3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) und Pferd.

Kurzübersicht für Derlin-3 Antikörper (C-Term) (ABIN2781869)

Target: Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Derlin-3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Derlin-3 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: DERL3 Antibody - C-terminal region

Sequenz: YYFLEDVFPN QPGGKRLLQT PGFLKLLLDA PAEDPNYLPL PEEQPGPHLP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DERL3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DERL3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44443-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Derlin-3

Target: Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))

Andere Bezeichnung: DERL3

Hintergrund:

Background Information: DERL3 belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL3 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]).[supplied by OMIM].

Gene Name: Der1-like domain family, member 3

Alternative Symbols: IZP6, LLN2, C22orf14, derlin-3

Protein Name: Derlin-3

Molekulargewicht: 27kDa

Gen-ID: 91319

NCBI Accession: NP_001002862

UniProt: Q96Q80

Pathways: ER-Nucleus Signaling