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M-CSF/CSF1 Antikörper (N-Term)

Dieses Anti-M-CSF/CSF1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von M-CSF/CSF1 in WB und IHC. Geeignet für Human, Ratte, Hund, Meerschweinchen und Kaninchen.
Produktnummer ABIN2781822

Kurzübersicht für M-CSF/CSF1 Antikörper (N-Term) (ABIN2781822)

Target

Alle M-CSF/CSF1 (CSF1) Antikörper anzeigen
M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Reaktivität

  • 97
  • 48
  • 15
  • 8
  • 6
  • 5
  • 2
  • 2
Human, Ratte, Hund, Meerschweinchen, Kaninchen

Wirt

  • 97
  • 16
  • 6
  • 2
  • 2
  • 1
Kaninchen

Klonalität

  • 96
  • 25
  • 2
Polyklonal

Konjugat

  • 65
  • 10
  • 9
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser M-CSF/CSF1 Antikörper ist unkonjugiert

Applikation

  • 82
  • 48
  • 40
  • 15
  • 13
  • 13
  • 13
  • 12
  • 10
  • 10
  • 10
  • 6
  • 4
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 9
    • 9
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    PPTTWLGSLL LLVCLLASRS ITEEVSEYCS HMIGSGHLQS LQRLIDSQME

    Homologie

    Dog: 85%, Guinea Pig: 85%, Human: 100%, Rabbit: 92%, Rat: 85%

    Produktmerkmale

    This is a rabbit polyclonal antibody against CSF1. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human CSF1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 438 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

    Andere Bezeichnung

    CSF1

    Hintergrund

    CSF1 is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. CSF1 may be involved in development of the placenta. The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Four transcript variants encoding three different isoforms have been found for this gene.
    Alias Symbols: MCSF, MGC31930, CSF-1
    Protein Interaction Partner: NOTCH2NL, SGTA, FHL3, GAB3, SOCS1, TNF, CSF1R, HLA-B, CSF1, SLA2, UBC, CBL, PIK3R2, SMARCA4,
    Protein Size: 438

    Molekulargewicht

    45 kDa

    Gen-ID

    1435

    NCBI Accession

    NM_172210, NP_757349

    UniProt

    Q5VVF3

    Pathways

    RTK Signalweg
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