M-CSF/CSF1 Antikörper (N-Term)
Kurzübersicht für M-CSF/CSF1 Antikörper (N-Term) (ABIN2781822)
Target
Alle M-CSF/CSF1 (CSF1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- PPTTWLGSLL LLVCLLASRS ITEEVSEYCS HMIGSGHLQS LQRLIDSQME
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Homologie
- Dog: 85%, Guinea Pig: 85%, Human: 100%, Rabbit: 92%, Rat: 85%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CSF1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CSF1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 438 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
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Andere Bezeichnung
- CSF1
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Hintergrund
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CSF1 is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. CSF1 may be involved in development of the placenta. The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Four transcript variants encoding three different isoforms have been found for this gene.
Alias Symbols: MCSF, MGC31930, CSF-1
Protein Interaction Partner: NOTCH2NL, SGTA, FHL3, GAB3, SOCS1, TNF, CSF1R, HLA-B, CSF1, SLA2, UBC, CBL, PIK3R2, SMARCA4,
Protein Size: 438 -
Molekulargewicht
- 45 kDa
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Gen-ID
- 1435
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NCBI Accession
- NM_172210, NP_757349
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UniProt
- Q5VVF3
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Pathways
- RTK Signalweg
Target
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