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FGG Antikörper (Middle Region)

Dieses Anti-FGG-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FGG in WB und IHC. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd und Zebrafisch (Danio rerio).
Produktnummer ABIN2781808

Kurzübersicht für FGG Antikörper (Middle Region) (ABIN2781808)

Target

Alle FGG Antikörper anzeigen
FGG (Fibrinogen gamma Chain (FGG))

Reaktivität

  • 90
  • 40
  • 39
  • 12
  • 6
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd, Zebrafisch (Danio rerio)

Wirt

  • 97
  • 20
  • 1
  • 1
Kaninchen

Klonalität

  • 90
  • 29
Polyklonal

Konjugat

  • 66
  • 16
  • 12
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FGG Antikörper ist unkonjugiert

Applikation

  • 98
  • 47
  • 34
  • 22
  • 20
  • 18
  • 16
  • 13
  • 13
  • 10
  • 8
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 10
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    GWTVFQKRLD GSVDFKKNWI QYKEGFGHLS PTGTTEFWLG NEKIHLISTQ

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

    Produktmerkmale

    This is a rabbit polyclonal antibody against FGG. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human FGG
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 437 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    FGG (Fibrinogen gamma Chain (FGG))

    Andere Bezeichnung

    FGG

    Hintergrund

    FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
    Alias Symbols: -
    Protein Interaction Partner: SUMO2, ASB12, ASB7, ASB6, FN1, VKORC1, KHDRBS2, SERPINA5, VTN, ITGB3, ICAM1, FGG, FGB, FGA, F13B, F13A1, ITGAM,
    Protein Size: 437

    Molekulargewicht

    46 kDa

    Gen-ID

    2266

    NCBI Accession

    NM_000509, NP_000500

    UniProt

    P02679
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