HFE Antikörper (N-Term)

Produktnummer ABIN2781799

Der Kaninchen Polyklonal anti-HFE Antikörper wird verwendet zum Nachweis von HFE in Proben von Human, Maus, Ratte, Rind (Kuh), Pferd und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für HFE Antikörper (N-Term) (ABIN2781799)

Target: HFE (Hemochromatosis (HFE))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HFE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HFE Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: HFE Antibody - N-terminal region

Sequenz: MGASEQDLGL SLFEALGYVD DQLFVFYDHE SRRVEPRTPW VSSRISSQMW

Homologie: Cow: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against HFE. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HFE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44283-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu HFE

Target: HFE (Hemochromatosis (HFE))

Andere Bezeichnung: HFE

Hintergrund:

Background Information: HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.

Gene Name: Hemochromatosis

Alternative Symbols: HH, HFE1, HLA-H, MVCD7, TFQTL2

Protein Name: Hereditary hemochromatosis protein

Molekulargewicht: 40

Gen-ID: 3077

NCBI Accession: NP_000401

UniProt: Q30201

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process