HFE Antikörper (AA 112-227)

Produktnummer ABIN7599746

Der Kaninchen Polyklonal anti-HFE Antikörper wird verwendet zum Nachweis von HFE in Proben von Maus und Ratte. Er wurde validiert für WB, ELISA, FACS und IHC.

Kurzübersicht für HFE Antikörper (AA 112-227) (ABIN7599746)

Target: HFE (Hemochromatosis (HFE))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HFE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)

Produktdetails anti-HFE Antikörper

Bindungsspezifität: AA 112-227

Verwendungszweck: Anti-Hfe Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Hfe Antibody. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Hfe recombinant protein (Position: N112-H227).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Mouse ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu HFE

Target: HFE (Hemochromatosis (HFE))

Andere Bezeichnung: Hfe

Hintergrund:

Background: Human homeostatic iron regulator protein, also known as the HFE protein (High FE2+), is a protein which in humans is encoded by the HFE gene. Enables transferrin receptor binding activity. Involved in positive regulation of gene expression. Acts upstream of or within hormone biosynthetic process and multicellular organismal iron ion homeostasis. Part of HFE-transferrin receptor complex. Is expressed in brain, choroid invagination, diencephalon roof plate, medulla oblongata part of 4th ventricle choroid plexus, and metencephalon part of 4th ventricle choroid plexus. Used to study hemochromatosis type 1. Human ortholog(s) of this gene implicated in several diseases, including acute porphyria (multiple), arthritis (multiple), bone marrow cancer (multiple), hemochromatosis (multiple), and liver disease (multiple). Orthologous to human HFE (homeostatic iron regulator).

Gene Full Name: homeostatic iron regulator

Molekulargewicht: 40-58 kDa

Gen-ID: 15216

UniProt: P70387

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process