G6PC Antikörper (N-Term)
(1 reference)-
- Target Alle G6PC Antikörper anzeigen
- G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser G6PC Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- NLVFKWILFG QRPYWWVLDT DYYSNTSVPL IKQFPVTCET GPGSPSGHAM
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 93%, Sheep: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against G6PC. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human G6PC
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anti-Glucose 6-Phosphatase, Catalytic (G6PC) (AA 123-149) antibody
G6PC Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB30027 unconjugated
anti-Glucose 6-Phosphatase, Catalytic (G6PC) (N-Term) antibodyG6PC Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
anti-Glucose 6-Phosphatase, Catalytic (G6PC) (N-Term) antibodyG6PC Reaktivität: Human, Hund WB Wirt: Kaninchen Polyclonal unconjugated
anti-Glucose 6-Phosphatase, Catalytic (G6PC) (AA 82-117) antibodyG6PC Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Glucose 6-Phosphatase, Catalytic (G6PC) antibodyG6PC Reaktivität: Human, Maus, Ratte ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 357 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and may contain up to 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Branched-chain amino acid supplementation reduces oxidative stress and prolongs survival in rats with advanced liver cirrhosis." in: PLoS ONE, Vol. 8, Issue 7, pp. e70309, (2013) (PubMed).
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: "Branched-chain amino acid supplementation reduces oxidative stress and prolongs survival in rats with advanced liver cirrhosis." in: PLoS ONE, Vol. 8, Issue 7, pp. e70309, (2013) (PubMed).
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- Target
- G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
- Andere Bezeichnung
- G6PC (G6PC Produkte)
- Hintergrund
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G6PC hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum.It forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I (von Gierke disease). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: G6PT, GSD1a, MGC163350, GSD1, G6PC1
Protein Interaction Partner: NSL1, SNX13, CDH16, FOXO1,
Protein Size: 357 - Molekulargewicht
- 40 kDa
- Gen-ID
- 2538
- NCBI Accession
- NM_000151, NP_000142
- UniProt
- P35575
- Pathways
- Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
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