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G6PC Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch G6PC in WB und IHC. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.
Produktnummer ABIN2781770

Kurzübersicht für G6PC Antikörper (N-Term) (ABIN2781770)

Target

Alle G6PC Antikörper anzeigen
G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))

Reaktivität

  • 47
  • 24
  • 23
  • 16
  • 14
  • 13
  • 1
  • 1
  • 1
Human

Wirt

  • 49
  • 3
Kaninchen

Klonalität

  • 49
  • 3
Polyklonal

Konjugat

  • 20
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser G6PC Antikörper ist unkonjugiert

Applikation

  • 38
  • 23
  • 20
  • 11
  • 11
  • 8
  • 8
  • 4
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 7
    • 6
    • 6
    • 6
    • 6
    • 2
    • 1
    N-Term

    Sequenz

    NLVFKWILFG QRPYWWVLDT DYYSNTSVPL IKQFPVTCET GPGSPSGHAM

    Homologie

    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 93%, Sheep: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against G6PC. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human G6PC
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 357 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and may contain up to 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Iwasa, Kobayashi, Mifuji-Moroka, Hara, Miyachi, Sugimoto, Tanaka, Fujita, Gabazza, Takei: "Branched-chain amino acid supplementation reduces oxidative stress and prolongs survival in rats with advanced liver cirrhosis." in: PLoS ONE, Vol. 8, Issue 7, pp. e70309, (2013) (PubMed).

  • Target

    G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))

    Andere Bezeichnung

    G6PC

    Hintergrund

    G6PC hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum.It forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I (von Gierke disease). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: G6PT, GSD1a, MGC163350, GSD1, G6PC1
    Protein Interaction Partner: NSL1, SNX13, CDH16, FOXO1,
    Protein Size: 357

    Molekulargewicht

    40 kDa

    Gen-ID

    2538

    NCBI Accession

    NM_000151, NP_000142

    UniProt

    P35575

    Pathways

    Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
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