G6PC Antikörper (N-Term)
Kurzübersicht für G6PC Antikörper (N-Term) (ABIN2781769)
Target
Alle G6PC Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- N-Term
-
Sequenz
- DFGIQSTRYL QVNYQDSQDW FILVSVIADL RNAFYVLFPI WFHLKETVGI
-
Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 85%, Rat: 86%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against G6pc. It was validated on Western Blot.
-
Aufreinigung
- Affinity Purified
-
Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
-
Kommentare
-
Antigen size: 357 AA
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
-
Berberine inhibits gluconeogenesis in spontaneous diabetic rats by regulating the AKT/MAPK/NO/cGMP/PKG signaling pathway." in: Molecular and cellular biochemistry, (2023) (PubMed).
: "Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates." in: Nature medicine, Vol. 23, Issue 4, pp. 439-449, (2017) (PubMed).
: "Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling." in: Nature communications, Vol. 7, pp. 10592, (2016) (PubMed).
: "
-
Berberine inhibits gluconeogenesis in spontaneous diabetic rats by regulating the AKT/MAPK/NO/cGMP/PKG signaling pathway." in: Molecular and cellular biochemistry, (2023) (PubMed).
-
- G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
-
Andere Bezeichnung
- G6pc
-
Hintergrund
-
G6pc hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. It forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.
Alias Symbols: AW107337, G6Pase, G6pt, Glc-6-Pase
Protein Interaction Partner: Ppargc1a, Foxo1, Sirt1,
Protein Size: 357 -
Molekulargewicht
- 40 kDa
-
Gen-ID
- 14377
-
NCBI Accession
- NM_008061, NP_032087
-
UniProt
- P35576
-
Pathways
- Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
Target
-