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G6PC Antikörper (N-Term)

Dieses Anti-G6PC-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von G6PC in WB. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd und Kaninchen. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.
Produktnummer ABIN2781769

Kurzübersicht für G6PC Antikörper (N-Term) (ABIN2781769)

Target

Alle G6PC Antikörper anzeigen
G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))

Reaktivität

Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt

  • 49
  • 3
Kaninchen

Klonalität

  • 49
  • 3
Polyklonal

Konjugat

  • 20
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser G6PC Antikörper ist unkonjugiert

Applikation

  • 38
  • 24
  • 20
  • 11
  • 11
  • 8
  • 8
  • 4
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 7
    • 6
    • 6
    • 6
    • 6
    • 2
    • 1
    N-Term

    Sequenz

    DFGIQSTRYL QVNYQDSQDW FILVSVIADL RNAFYVLFPI WFHLKETVGI

    Homologie

    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 85%, Rat: 86%

    Produktmerkmale

    This is a rabbit polyclonal antibody against G6pc. It was validated on Western Blot.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide corresponding to a region of Mouse
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 357 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lu, Wang, Jiang, Zhang, Wang, Sha, Chen, Lei, Liu: "Berberine inhibits gluconeogenesis in spontaneous diabetic rats by regulating the AKT/MAPK/NO/cGMP/PKG signaling pathway." in: Molecular and cellular biochemistry, (2023) (PubMed).

    Wang, Ji, Zhang, Zhao, Yan, Zhang, Shen, Yang, Fang, Tian, Zhu, Gong, Zhang, Wei, Wang, Li, Wan, Xie, She, Wang, Huang, Li: "Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates." in: Nature medicine, Vol. 23, Issue 4, pp. 439-449, (2017) (PubMed).

    Wang, Zhang, Luo, Jiang, Zhang, Guo, Zhao, Zhu, Zhang, Yang, Li: "Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling." in: Nature communications, Vol. 7, pp. 10592, (2016) (PubMed).

  • Target

    G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))

    Andere Bezeichnung

    G6pc

    Hintergrund

    G6pc hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. It forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.
    Alias Symbols: AW107337, G6Pase, G6pt, Glc-6-Pase
    Protein Interaction Partner: Ppargc1a, Foxo1, Sirt1,
    Protein Size: 357

    Molekulargewicht

    40 kDa

    Gen-ID

    14377

    NCBI Accession

    NM_008061, NP_032087

    UniProt

    P35576

    Pathways

    Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
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