ORCTL-2/SLC22A18 Antikörper (N-Term)

Produktnummer ABIN2781574

Produktdetails anti-ORCTL-2/SLC22A18 Antikörper

Target: ORCTL-2/SLC22A18 (SLC22A18) (Solute Carrier Family 22 Member 18 (SLC22A18))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORCTL-2/SLC22A18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AASSPALPGV YLLFASRLPG ALMHTLPAAQ MVITDLSAPE ERPAALGRLG

Homologie: Cow: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SLC22A18. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC22A18

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 424 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ORCTL-2/SLC22A18

Target: ORCTL-2/SLC22A18 (SLC22A18) (Solute Carrier Family 22 Member 18 (SLC22A18))

Andere Bezeichnung: SLC22A18 (SLC22A18 Produkte)

Synonyme: MGC123168 antikoerper, zgc:123168 antikoerper, BWR1A antikoerper, BWSCR1A antikoerper, HET antikoerper, IMPT1 antikoerper, ITM antikoerper, ORCTL2 antikoerper, SLC22A1L antikoerper, TSSC5 antikoerper, p45-BWR1A antikoerper, AW260131 antikoerper, Impt1 antikoerper, Orctl2 antikoerper, Slc22a1l antikoerper, solute carrier family 22, member 18 antikoerper, solute carrier family 22 member 18 antikoerper, solute carrier family 22 (organic cation transporter), member 18 antikoerper, slc22a18 antikoerper, SLC22A18 antikoerper, Slc22a18 antikoerper

Hintergrund: This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as the transport of chloroquine- and quinidine-related compounds in the kidney.This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as the transport of chloroquine- and quinidine-related compounds in the kidney. Two alternative transcripts encoding the same isoform have been described.
Alias Symbols: BWR1A, BWSCR1A, DKFZp667A184, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5, p45-BWR1A
Protein Interaction Partner: RNF167, UBC,
Protein Size: 424

Molekulargewicht: 45 kDa

Gen-ID: 5002

NCBI Accession: NM_002555, NP_002546

UniProt: Q96BI1