ORCTL-2/SLC22A18 Antikörper (AA 359-408)

Produktnummer ABIN1534063

Der Kaninchen Polyklonal anti-ORCTL-2/SLC22A18 Antikörper wird verwendet zum Nachweis von ORCTL-2/SLC22A18 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA und IF.

Kurzübersicht für ORCTL-2/SLC22A18 Antikörper (AA 359-408) (ABIN1534063)

Target: ORCTL-2/SLC22A18 (SLC22A18) (Solute Carrier Family 22 Member 18 (SLC22A18))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORCTL-2/SLC22A18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-ORCTL-2/SLC22A18 Antikörper

Bindungsspezifität: AA 359-408

Verwendungszweck: ORCTL2 Antibody

Spezifität: ORCTL2 Polyclonal Antibody detects endogenous levels of ORCTL2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ORCTL-2. AA range:359-408

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu ORCTL-2/SLC22A18

Target: ORCTL-2/SLC22A18 (SLC22A18) (Solute Carrier Family 22 Member 18 (SLC22A18))

Andere Bezeichnung: ORCTL-2

Hintergrund:

Synonyms: SLC22A18; BWR1A; BWSCR1A; HET; IMPT1; ITM; ORCTL2; SLC22A1L; TSSC5; Solute carrier family 22 member 18; Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein; Efflux transporter-like protein; Imprinted multi-membrane-spa

Background: This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms' tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Several alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2015],

Gene Name: SLC22A18

Protein Name: Solute carrier family 22 member 18

Molekulargewicht: 43 kDa

Gen-ID: 5002

OMIM: 602631

UniProt: Q96BI1