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GCHFR Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-GCHFR Antikörper wurde für WB validiert. Er ist geeignet, GCHFR in Proben von Human, Ratte, Maus, Pferd, Rind (Kuh), Meerschweinchen und Kaninchen zu detektieren.
Produktnummer ABIN2781329

Kurzübersicht für GCHFR Antikörper (N-Term) (ABIN2781329)

Target

Alle GCHFR Antikörper anzeigen
GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Reaktivität

Human, Ratte, Maus, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt

  • 47
  • 5
Kaninchen

Klonalität

  • 47
  • 5
Polyklonal

Konjugat

  • 21
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GCHFR Antikörper ist unkonjugiert

Applikation

  • 21
  • 19
  • 13
  • 13
  • 11
  • 4
  • 3
  • 3
  • 3
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 10
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    MPYLLISTQI RMEVGPTMVG DEQSDPELMQ HLGASKRRAL GNNFYEYYVD

    Homologie

    Cow: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 86%

    Produktmerkmale

    This is a rabbit polyclonal antibody against GCHFR. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human GCHFR
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 84 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

    Andere Bezeichnung

    GCHFR

    Hintergrund

    GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.
    Alias Symbols: GFRP, HsT16933, MGC138467, MGC138469, P35
    Protein Interaction Partner: GCH1, MYC, EBNA-LP, GCHFR,
    Protein Size: 84

    Molekulargewicht

    10 kDa

    Gen-ID

    2644

    NCBI Accession

    NM_005258, NP_005249

    UniProt

    P30047
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