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M6PR Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch M6PR in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen und Pferd.
Produktnummer ABIN2781302

Kurzübersicht für M6PR Antikörper (N-Term) (ABIN2781302)

Target

Alle M6PR Antikörper anzeigen
M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Reaktivität

Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd

Wirt

  • 36
  • 6
  • 2
  • 1
Kaninchen

Klonalität

  • 32
  • 13
Polyklonal

Konjugat

  • 23
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser M6PR Antikörper ist unkonjugiert

Applikation

  • 21
  • 16
  • 12
  • 7
  • 6
  • 6
  • 5
  • 2
  • 2
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    RLKPLFNKSF ESTVGQGSDT YIYIFRVCRE AGNHTSGAGL VQINKSNGKE

    Homologie

    Cow: 85%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against M6PR. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human M6PR
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 277 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

    Andere Bezeichnung

    M6PR

    Hintergrund

    M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.The protein encoded by this gene is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.
    Alias Symbols: CD-MPR, FLJ32994, MPR46, SMPR, MPR 46, MPR-46
    Protein Interaction Partner: FBXO6, ATP4A, SNRPGP15, HPDL, RPS28, RPL37A, RPL6, RANBP2, NDUFS4, NDUFB4, ACP2, ACOX1, GGA3, GGA1, JUN, UBC, GGA2, PLIN3, REN,
    Protein Size: 277

    Molekulargewicht

    28 kDa

    Gen-ID

    4074

    NCBI Accession

    NM_002355, NP_002346

    UniProt

    P20645
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