PHF1 Antikörper (N-Term)

Produktnummer ABIN2781208

Der Kaninchen Polyklonal Anti-PHF1-Antikörper wurde für WB validiert. Er ist geeignet, PHF1 in Proben von Human, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen und Pferd zu detektieren.

Kurzübersicht für PHF1 Antikörper (N-Term) (ABIN2781208)

Target: PHF1 (PHD Finger Protein 1 (PHF1))

Reaktivität: Human, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PHF1 Antikörper

Bindungsspezifität: N-Term

Sequenz: MAQPPRLSRS GASSLWDPAS PAPTSGPRPR LWEGQDVLAR WTDGLLYLGT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PHF1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PHF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 567 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PHF1

Target: PHF1 (PHD Finger Protein 1 (PHF1))

Andere Bezeichnung: PHF1

Hintergrund: PHF1 has significant sequence similarity with Drosophila Polycomblike. It contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. This gene encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. Two transcript variants have been found for this gene.This gene encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. Two transcript variants have been found for this gene.
Alias Symbols: PHF2, PCL1, MTF2L2
Protein Interaction Partner: ATXN7L1, BIRC7, VAC14, HSD17B14, RBPMS, CALCOCO2, PDLIM7, TFCP2, NAB2, TRIM23, SUZ12, EZH2, NEK6, TP53, SUMO1, HIC1, ELAVL1, UBC, RAD50, NCR1, EED, SMC1A, XRCC5, RBBP7, XRCC6, DHX9, HIST1H3J, HIST1H3G, HIST1H3I, HIST1H3E, HIST1H3C, HIST1H3A, HIST1H3F, HIS
Protein Size: 567

Molekulargewicht: 62 kDa

Gen-ID: 5252

NCBI Accession: NM_024165, NP_077084

UniProt: O43189