FOXA2 Antikörper (N-Term)

Produktnummer ABIN2781158

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FOXA2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Hund, Kaninchen, Meerschweinchen und Rind (Kuh).

Kurzübersicht für FOXA2 Antikörper (N-Term) (ABIN2781158)

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Reaktivität: Human, Ratte, Maus, Hund, Kaninchen, Meerschweinchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FOXA2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: FOXA2 Antibody - N-terminal region

Sequenz: MLGAVKMEGH EPSDWSSYYA EPEGYSSVSN MNAGLGMNGM NTYMSMSAAA

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FOXA2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FOXA2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100823

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FOXA2

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Andere Bezeichnung: FOXA2

Hintergrund:

Background Information: FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young.This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.

Gene Name: Forkhead box A2

Alternative Symbols: HNF3B, TCF3B, HNF-3-beta

Protein Name: Hepatocyte nuclear factor 3-beta

Molekulargewicht: 50kDa

Gen-ID: 3170

NCBI Accession: NP_710141

UniProt: Q9Y261

Pathways: Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process