MNT Antikörper (N-Term)

Produktnummer ABIN405231

Dieser Anti-MNT Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von MNT in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Schwein und Saccharomyces cerevisiae.

Kurzübersicht für MNT Antikörper (N-Term) (ABIN405231)

Target: MNT (MNT, MAX Dimerization Protein (MNT))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Schwein, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MNT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MNT Antikörper

Bindungsspezifität: N-Term

Sequenz: SIETLLEAAR FLEWQAQQQQ RAREEQERLR LEQEREQEQK KANSLARLAH

Homologie: Cow: 93%, Dog: 93%, Horse: 80%, Human: 100%, Mouse: 93%, Pig: 80%, Rabbit: 93%, Rat: 93%, Yeast: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against MNT. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MNT

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 582 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MNT

Target: MNT (MNT, MAX Dimerization Protein (MNT))

Andere Bezeichnung: MNT

Hintergrund: The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. MNT is a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MAD6, MXD6, ROX, bHLHd3
Protein Interaction Partner: Dlg4, ELAVL1, CEBPA, MAX, MAD1L1, MYC, HDAC1, SIN3A, MNT, MLX, HMGB1,
Protein Size: 582

Molekulargewicht: 62 kDa

Gen-ID: 4335

NCBI Accession: NM_020310, NP_064706

UniProt: Q99583

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation