KLHL3 Antikörper (Middle Region)

Produktnummer ABIN2781024

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch KLHL3 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Kaninchen, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für KLHL3 Antikörper (Middle Region) (ABIN2781024)

Target: KLHL3 (Kelch-Like 3 (KLHL3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Kaninchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLHL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KLHL3 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: KLHL3 Antibody - middle region

Sequenz: LYVVGGDDGS CNLASVEYYN PVTDKWTLLP TNMSTGRSYA GVAVIHKSL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against KLHL3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KLHL3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39277-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu KLHL3

Target: KLHL3 (Kelch-Like 3 (KLHL3))

Andere Bezeichnung: KLHL3

Hintergrund:

Background Information: KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77 % similarity with Drosophila kelch and 89 % similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q, however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.

Gene Name: Kelch-like 3 (Drosophila)

Alternative Symbols: PHA2D

Protein Name: Kelch-like protein 3

Molekulargewicht: 65kDa

Gen-ID: 26249

NCBI Accession: NP_059111

UniProt: Q9UH77