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KLHL3 Antikörper

KLHL3 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7257377
  • Target Alle KLHL3 Antikörper anzeigen
    KLHL3 (Kelch-Like 3 (KLHL3))
    Reaktivität
    • 50
    • 8
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 48
    • 2
    Kaninchen
    Klonalität
    • 50
    Polyklonal
    Konjugat
    • 22
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KLHL3 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 24
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human KLHL3 (NP_059111.2).
    Isotyp
    IgG
    Top Product
    Discover our top product KLHL3 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    KLHL3 (Kelch-Like 3 (KLHL3))
    Andere Bezeichnung
    KLHL3 (KLHL3 Produkte)
    Synonyme
    7530408C15Rik antikoerper, AI430941 antikoerper, EG627648 antikoerper, PHA2D antikoerper, RGD1565218 antikoerper, kelch like family member 3 antikoerper, kelch-like 3 antikoerper, kelch-like family member 3 antikoerper, KLHL3 antikoerper, Klhl3 antikoerper
    Hintergrund
    This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D), a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    Molekulargewicht

    Observed_MW: 75 kDa

    Calculated_MW: 55 kDa/61 kDa/64 kDa

    Gen-ID
    26249
    UniProt
    Q9UH77
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