SUFUH Antikörper (Middle Region)

Produktnummer ABIN2780999

Der Kaninchen Polyklonal Anti-SUFUH-Antikörper wurde für WB und IHC validiert. Er ist geeignet, SUFUH in Proben von Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für SUFUH Antikörper (Middle Region) (ABIN2780999)

Target: SUFUH (Suppressor of Fused Homolog (SUFUH))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUFUH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SUFUH Antikörper

Bindungsspezifität: Middle Region

Sequenz: LQILLTEEFV EKMLEDLEDL TSPEEFKLPK EYSWPEKKLK VSILPDVVFD

Homologie: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SUFU. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SUFU

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 484 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SUFUH

Target: SUFUH (Suppressor of Fused Homolog (SUFUH))

Andere Bezeichnung: SUFU

Hintergrund: SUFU is a component of the Sonic hedgehog (SHH, MIM 600725)/Patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes.SUFU encodes a component of the sonic hedgehog (SHH, MIM 600725)/patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945, BCNS, MIM 109400, and GCPS, MIM 175700).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PRO1280, SUFUH, SUFUXL
Protein Interaction Partner: ZNF747, FBXL17, GLIS3, UBC, GLI1, HDX, SAP18, RCN3, PIAS1, PEX26, ZNF764, STK36, ZNF446, QPRT, SETDB1, MID1IP1, RNF19A, SUFU, ZNF219, ZNF263, BTRC, LAMTOR3, NCOA3, HMGA1, GLI3, GLI2, HNRNPA1, LGALS3, RBPJ,
Protein Size: 484

Molekulargewicht: 54 kDa

Gen-ID: 51684

NCBI Accession: NM_016169, NP_057253

UniProt: Q9UMX1

Pathways: Hedgehog Signalweg, Tube Formation, Maintenance of Protein Location