ARNT2 Antikörper (N-Term)

Produktnummer ABIN2780951

Der Kaninchen Polyklonal anti-ARNT2 Antikörper (ABIN2780951) detektiert spezifisch ARNT2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen, Pferd, Schaf und Kaninchen.

Kurzübersicht für ARNT2 Antikörper (N-Term) (ABIN2780951)

Target: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen, Pferd, Schaf, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARNT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ARNT2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: ARNT2 Antibody - N-terminal region

Sequenz: VTLPVAPMAA TGQVRMAGAM PARGGKRRSG MDFDDEDGEG PSKFSRENHS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ARNT2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ARNT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39146-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu ARNT2

Target: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Andere Bezeichnung: ARNT2

Hintergrund:

Background Information: This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.

Gene Name: aryl-hydrocarbon receptor nuclear translocator 2

Alternative Symbols: WEDAS, bHLHe1

Protein Name: ARNT2 protein EMBL AAH51335.1

Molekulargewicht: 23kDa

Gen-ID: 9915

UniProt: Q86TN1

Pathways: Warburg Effekt