BRD7 Antikörper (C-Term)
Kurzübersicht für BRD7 Antikörper (C-Term) (ABIN2780896)
Target
Alle BRD7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- KELAQQVTPG DIVSTYGVRK AMGISIPSPV MENNFVDLTE DTEEPKKTDV
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Homologie
- Dog: 86%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Rabbit: 79%, Rat: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against BRD7. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human BRD7
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 651 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Yersinia YopJ inhibits pro-inflammatory molecule expression in human bronchial epithelial cells." in: Respiratory physiology & neurobiology, Vol. 140, Issue 1, pp. 89-97, (2004) (PubMed).
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: "Yersinia YopJ inhibits pro-inflammatory molecule expression in human bronchial epithelial cells." in: Respiratory physiology & neurobiology, Vol. 140, Issue 1, pp. 89-97, (2004) (PubMed).
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- BRD7 (Bromodomain Containing 7 (BRD7))
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Andere Bezeichnung
- BRD7
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Hintergrund
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BRD7 is an activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. It induces dephosphorylation of GSK3B at 'Tyr-216'.
Alias Symbols: BP75, CELTIX1, NAG4
Protein Interaction Partner: UBC, Dvl1, HIST2H3C, BRD2, NEFL, BARD1, LRIF1, HAP1, TFAP4, TRIM24, SUMO2, SMARCE1, SMARCD1, SMARCC2, Bcl7b, CHD7, ARID2, RBFOX2, BCL7C, SMARCC1, SMARCA4, PCBD1, POU2F1, MYC, BRCA1, BHLHE40, HIST2H4A, HIST2H3A, BTBD2, RIF1, HNRNPUL1, HIST1H2AL, AGR2, PSMD
Protein Size: 651 -
Molekulargewicht
- 74 kDa
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Gen-ID
- 29117
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NCBI Accession
- NM_013263, NP_037395
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UniProt
- Q9NPI1
Target
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