LDOC1 Antikörper (N-Term)

Produktnummer ABIN405190

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch LDOC1 in IHC und WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen und Pferd.

Kurzübersicht für LDOC1 Antikörper (N-Term) (ABIN405190)

Target: LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LDOC1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails anti-LDOC1 Antikörper

Bindungsspezifität: N-Term

Sequenz: MVDELVLLLH ALLMRHRALS IENSQLMEQL RLLVCERASL LRQVRPPSCP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Rabbit: 100%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against LDOC1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LDOC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 146 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu LDOC1

Target: LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))

Andere Bezeichnung: LDOC1

Hintergrund: LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.
Alias Symbols: BCUR1, Mar7, Mart7
Protein Interaction Partner: LENG1, TTC23, MEAF6, SH2D4A, CTNNBL1, DPPA4, FAM90A1, C1orf109, FAM208B, TBC1D7, PRPF31, LDOC1, PEG10, NXF1, ZBTB24, HDAC4, ATP6V1G1, HGS, LATS1, RAB29, TNNT1, TMSB4XP1, SDCBP, DPF2, PSMA1, MFAP1, BARD1, ATF4, AES, ZNF774, ZNF564, HAUS1, ZGPAT, CCDC33, IN
Protein Size: 146

Molekulargewicht: 17 kDa

Gen-ID: 23641

NCBI Accession: NM_012317, NP_036449

UniProt: O95751