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LDOC1 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch LDOC1 in IHC und WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen und Pferd.
Produktnummer ABIN2780876

Kurzübersicht für LDOC1 Antikörper (N-Term) (ABIN2780876)

Target

Alle LDOC1 Antikörper anzeigen
LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))

Reaktivität

  • 38
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd

Wirt

  • 36
  • 7
Kaninchen

Klonalität

  • 39
  • 4
Polyklonal

Konjugat

  • 23
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser LDOC1 Antikörper ist unkonjugiert

Applikation

  • 17
  • 13
  • 13
  • 11
  • 10
  • 9
  • 8
  • 5
  • 3
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    MVDELVLLLH ALLMRHRALS IENSQLMEQL RLLVCERASL LRQVRPPSCP

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Rabbit: 100%, Rat: 79%

    Produktmerkmale

    This is a rabbit polyclonal antibody against LDOC1. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human LDOC1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 146 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))

    Andere Bezeichnung

    LDOC1

    Hintergrund

    LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.
    Alias Symbols: BCUR1, Mar7, Mart7
    Protein Interaction Partner: LENG1, TTC23, MEAF6, SH2D4A, CTNNBL1, DPPA4, FAM90A1, C1orf109, FAM208B, TBC1D7, PRPF31, LDOC1, PEG10, NXF1, ZBTB24, HDAC4, ATP6V1G1, HGS, LATS1, RAB29, TNNT1, TMSB4XP1, SDCBP, DPF2, PSMA1, MFAP1, BARD1, ATF4, AES, ZNF774, ZNF564, HAUS1, ZGPAT, CCDC33, IN
    Protein Size: 146

    Molekulargewicht

    17 kDa

    Gen-ID

    23641

    NCBI Accession

    NM_012317, NP_036449

    UniProt

    O95751
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