LDOC1 Antikörper (N-Term)
Kurzübersicht für LDOC1 Antikörper (N-Term) (ABIN2780876)
Target
Alle LDOC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- N-Term
-
Sequenz
- MVDELVLLLH ALLMRHRALS IENSQLMEQL RLLVCERASL LRQVRPPSCP
-
Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Rabbit: 100%, Rat: 79%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against LDOC1. It was validated on Western Blot using a cell lysate as a positive control.
-
Aufreinigung
- Affinity Purified
-
Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human LDOC1
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
-
Kommentare
-
Antigen size: 146 AA
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))
-
Andere Bezeichnung
- LDOC1
-
Hintergrund
-
LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.
Alias Symbols: BCUR1, Mar7, Mart7
Protein Interaction Partner: LENG1, TTC23, MEAF6, SH2D4A, CTNNBL1, DPPA4, FAM90A1, C1orf109, FAM208B, TBC1D7, PRPF31, LDOC1, PEG10, NXF1, ZBTB24, HDAC4, ATP6V1G1, HGS, LATS1, RAB29, TNNT1, TMSB4XP1, SDCBP, DPF2, PSMA1, MFAP1, BARD1, ATF4, AES, ZNF774, ZNF564, HAUS1, ZGPAT, CCDC33, IN
Protein Size: 146 -
Molekulargewicht
- 17 kDa
-
Gen-ID
- 23641
-
NCBI Accession
- NM_012317, NP_036449
-
UniProt
- O95751
Target
-