DP1 Antikörper (N-Term)
Kurzübersicht für DP1 Antikörper (N-Term) (ABIN2780829)
Target
Alle DP1 (TFDP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- NLSPGKGVVS LVAVHPSTVN TLGKQLLPKT FGQSNVNITQ QVVIGTPQRP
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against Tfdp1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 410 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))
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Andere Bezeichnung
- Tfdp1
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Hintergrund
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Tfdp1 can stimulate E2F-dependent transcription. Tfdp1 binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.
Alias Symbols: Dp1, Drtf1
Protein Interaction Partner: L3mbtl2, Sertad1, SERTAD2, E2f1, Rnf2, Epc1, E2F6,
Protein Size: 410 -
Molekulargewicht
- 45 kDa
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Gen-ID
- 21781
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NCBI Accession
- NM_009361, NP_033387
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UniProt
- Q08639
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Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
Target
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