ZBTB33 Antikörper (N-Term)

Produktnummer ABIN2780808

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ZBTB33 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen und Kaninchen.

Kurzübersicht für ZBTB33 Antikörper (N-Term) (ABIN2780808)

Target: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZBTB33 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ZBTB33 Antikörper

Bindungsspezifität: N-Term

Sequenz: MESRKLISAT DIQYSGSLLN SLNEQRGHGL FCDVTVIVED RKFRAHKNIL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ZBTB33. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZBTB33

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 672 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ZBTB33

Target: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Andere Bezeichnung: ZBTB33

Hintergrund: ZBTB33 is a transcriptional regulator with bimodal DNA-binding specificity. ZBTB33 binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3'. ZBTB33 recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway. It may also activate transcription of a subset of target genes by the recruitment of CTNND2.
Alias Symbols: ZNF348, ZNF-kaiso
Protein Interaction Partner: HUWE1, SUMO2, SUMO3, CBFA2T3, LMNA, UBC, TCF7L2, KPNA2, CTNND1, CTNNB1, CTCF, ELAVL1, CTNND2, WDR48, NCOR1, ZBTB33, HDAC3, WNT11, S100A4, MMP7,
Protein Size: 672

Molekulargewicht: 74 kDa

Gen-ID: 10009

NCBI Accession: NM_006777, NP_006768

UniProt: Q86T24