HDAC6 Antikörper (C-Term)

Produktnummer ABIN2780739

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HDAC6 in WB, IHC und ChIP. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Schwein, Kaninchen, Hund, Meerschweinchen, Rind (Kuh) und Pferd.

Kurzübersicht für HDAC6 Antikörper (C-Term) (ABIN2780739)

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Reaktivität: Human, Maus, Ratte, Schwein, Kaninchen, Hund, Meerschweinchen, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Produktdetails anti-HDAC6 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Hdac6 Antibody - C-terminal region

Sequenz: VCHHEASEHP LVLSCVDLST WCYVCQAYVH HEDLQDVKNA AHQNKFGEDM

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 85%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against Hdac6. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Hdac6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38730-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu HDAC6

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Andere Bezeichnung: Hdac6

Hintergrund:

Background Information: Hdac6 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Hdac6 plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.

Gene Name: Histone deacetylase 6

Alternative Symbols: Hd6, Sfc, Sfc6, mHDA, Hdac5, mHDA2

Protein Name: Histone deacetylase 6

Molekulargewicht: 126kDa

Gen-ID: 15185

NCBI Accession: NP_034543

UniProt: Q9Z2V5

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling