FOXO4 Antikörper (C-Term)

Produktnummer ABIN2780728

Der Kaninchen Polyklonal anti-FOXO4 Antikörper (ABIN2780728) detektiert spezifisch FOXO4 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen und Kaninchen.

Kurzübersicht für FOXO4 Antikörper (C-Term) (ABIN2780728)

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXO4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FOXO4 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Foxo4 Antibody - C-terminal region

Sequenz: PPVMAGAPIP KVLGTPVLAS PTEDSSHDRM PQDLDLDMYM ENLECDMDNI

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Foxo4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38710-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FOXO4

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Andere Bezeichnung: Foxo4

Hintergrund:

Background Information: Foxo4 is a transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. It down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. It represses smooth muscle cell differentiation by inhibiting the transcriptional coactivator activity of myocardin.

Gene Name: Forkhead box O4

Alternative Symbols: af, Fox, Mll, afx, Afxh, Mllt7

Protein Name: Histone acetyltransferase KAT5

Molekulargewicht: 54kDa

Gen-ID: 54601

NCBI Accession: NP_001005872

UniProt: Q99MK2

Pathways: Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation