AFT1 Antikörper (C-Term)

Produktnummer ABIN309902

Produktdetails anti-AFT1 Antikörper

Target: AFT1 (Activating Transcription Factor 1 (AFT1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AFT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: KNREAARECR RKKKEYVKCL ENRVAVLENQ NKTLIEELKT LKDLYSNKSV

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 77%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ATF1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ATF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 271 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AFT1

Target: AFT1 (Activating Transcription Factor 1 (AFT1))

Andere Bezeichnung: ATF1 (AFT1 Produkte)

Hintergrund: ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT [AC] [AG]-3'), a sequence present in many viral and cellular promoters. ATF1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes.
Alias Symbols: EWS-ATF1, FUS/ATF-1, TREB36
Protein Interaction Partner: UBC, SRA1, FOSL2, GABPB1, GABPA, EDF1, HNF1B, RPS6KA5, CAMK1, RPS6KA4, CAMK2G, PRKACA, CREBBP, SPI1, JUN, CREM, CREB1, ATF1, CSNK2A2, CSNK2A1, BRCA1, CSNK2B, CAMK2A, FOSL1,
Protein Size: 271

Molekulargewicht: 29 kDa

Gen-ID: 466

NCBI Accession: NM_005171, NP_005162

UniProt: P18846

Pathways: Neurotrophin Signalübertragung, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades