PHOX2A Antikörper (C-Term)

Produktnummer ABIN2780651

Produktdetails anti-PHOX2A Antikörper

Target: PHOX2A (Paired-Like Homeobox 2a (PHOX2A))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHOX2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VAGGGGGGPG AGAAELLKAW QPAESGPGPF SGVLSSFHRK PGPALKTNLF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PHOX2A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PHOX2A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 284 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PHOX2A

Target: PHOX2A (Paired-Like Homeobox 2a (PHOX2A))

Andere Bezeichnung: PHOX2A (PHOX2A Produkte)

Hintergrund: PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.
Alias Symbols: ARIX, CFEOM2, FEOM2, MGC52227, NCAM2, PMX2A
Protein Interaction Partner: SP1, PHOX2A, HAND2, PRKACA, ATF6B, CREBBP, JUN,
Protein Size: 284

Molekulargewicht: 30 kDa

Gen-ID: 401

NCBI Accession: NM_005169, NP_005160

UniProt: O14813