Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PHOX2A Antikörper (N-Term)

PHOX2A Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777426
  • Target Alle PHOX2A Antikörper anzeigen
    PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
    Bindungsspezifität
    • 15
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 31
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 27
    • 3
    • 1
    Kaninchen
    Klonalität
    • 29
    • 2
    Polyklonal
    Konjugat
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PHOX2A Antikörper ist unkonjugiert
    Applikation
    • 25
    • 13
    • 13
    • 11
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    AVPYKFFPEP SGLHEKRKQR RIRTTFTSAQ LKELERVFAE THYPDIYTRE
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PHOX2A. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PHOX2A
    Top Product
    Discover our top product PHOX2A Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 284 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
    Andere Bezeichnung
    PHOX2A (PHOX2A Produkte)
    Synonyme
    ARIX antikoerper, CFEOM2 antikoerper, FEOM2 antikoerper, NCAM2 antikoerper, PMX2A antikoerper, Arix antikoerper, Phox2 antikoerper, Pmx2 antikoerper, Pmx2a antikoerper, arix antikoerper, sou antikoerper, zgc:77364 antikoerper, phox2 antikoerper, xphox2a antikoerper, paired like homeobox 2a antikoerper, paired-like homeobox 2a antikoerper, paired like homeobox 2a S homeolog antikoerper, PHOX2A antikoerper, Phox2a antikoerper, phox2a antikoerper, phox2a.S antikoerper
    Hintergrund
    PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ARIX, CFEOM2, FEOM2, MGC52227, NCAM2, PMX2A
    Protein Interaction Partner: SP1, PHOX2A, HAND2, PRKACA, ATF6B, CREBBP, JUN,
    Protein Size: 284
    Molekulargewicht
    30 kDa
    Gen-ID
    401
    NCBI Accession
    NM_005169, NP_005160
    UniProt
    O14813
Sie sind hier:
Kundenservice