PHOX2A Antikörper (C-Term)

Produktnummer ABIN6991686

Produktdetails anti-PHOX2A Antikörper

Target: PHOX2A (Paired-Like Homeobox 2a (PHOX2A))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHOX2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: PHOX2A antibody is predicted to not cross-react with other paired homeobox family members.

Aufreinigung: PHOX2A Antibody is affinity chromatography purified via peptide column.

Immunogen: PHOX2A antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human PHOX2A. The immunogen is located within the last 50 amino acids of PHOX2A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PHOX2A antibody can be used for detection of PHOX2A by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PHOX2A Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PHOX2A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PHOX2A

Target: PHOX2A (Paired-Like Homeobox 2a (PHOX2A))

Andere Bezeichnung: PHOX2A (PHOX2A Produkte)

Synonyme: ARIX antikoerper, CFEOM2 antikoerper, FEOM2 antikoerper, NCAM2 antikoerper, PMX2A antikoerper, Arix antikoerper, Phox2 antikoerper, Pmx2 antikoerper, Pmx2a antikoerper, arix antikoerper, sou antikoerper, zgc:77364 antikoerper, phox2 antikoerper, xphox2a antikoerper, paired like homeobox 2a antikoerper, paired-like homeobox 2a antikoerper, paired like homeobox 2a S homeolog antikoerper, PHOX2A antikoerper, Phox2a antikoerper, phox2a antikoerper, phox2a.S antikoerper

Hintergrund: PHOX2A Antibody: PHOX2A and PHOX2B (Paired mesoderm homeobox protein) are closely related, paired-homeodomain transcription factors that function as determinants of the noradrenergic phenotype during embryogenesis. PHOX2 proteins are crucial for the regulation of endogenous hydroxylases in neural crest cells and promote sympathetic neuron generation. Human PHOX2B contains one DNA binding homeobox domain and is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain. In contrast, PHOX2A controls only the differentiation of the main noradrenergic center of the brain. Regulation of PHOX2 may have therapeutic utility in aging or disorders involving degeneration of noradrenergic neurons.

Gen-ID: 401

NCBI Accession: NP_005160

UniProt: O14813