CDK5 Antikörper (C-Term)

Produktnummer ABIN2780626

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CDK5 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Schwein, Hund, Schaf, Pferd, Kaninchen, Meerschweinchen und Saccharomyces cerevisiae.

Kurzübersicht für CDK5 Antikörper (C-Term) (ABIN2780626)

Target: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Schwein, Hund, Schaf, Pferd, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CDK5 Antikörper

Bindungsspezifität: C-Term

Sequenz: MYPATTSLVN VVPKLNATGR DLLQNLLKCN PVQRISAEEA LQHPYFSDFC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 79%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CDK5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CDK5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 292 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CDK5

Target: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Andere Bezeichnung: CDK5

Hintergrund: CDK5 is probably involved in the control of the cell cycle. CDK5 can interact with d1 and d3-type G1 cyclins and phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. CDK5 can also interacts with p35 which activates the kinase
Alias Symbols: PSSALRE
Protein Interaction Partner: CHFR, CCND2, CDKN1A, EGFR, UBC, DCLK3, CDK5, CCNE1, CDK5R1, CABLES1, CABLES2, STIP1, CDKN1B, CCND3, CCNB1, C2CD5, KIAA0195, FIBP, PPARG, CDK18, HSP90AB1, HSP90AA1, HIST1H1B, GLUD1, CDK3, CDC25B, CCT6A, CCNA2, CCT3, TCP1, CCT5, CDC37, CCT8, CCT2, CCT4, CCT
Protein Size: 292

Molekulargewicht: 33 kDa

Gen-ID: 1020

NCBI Accession: NM_004935, NP_004926

UniProt: Q00535

Pathways: Zellzyklus, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis