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KLF4 Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KLF4 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Kaninchen, Meerschweinchen und Zebrafisch (Danio rerio) und wurde in 1 Publikation erwähnt.
Produktnummer ABIN2780577

Kurzübersicht für KLF4 Antikörper (C-Term) (ABIN2780577)

Target

Alle KLF4 Antikörper anzeigen
KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Reaktivität

  • 107
  • 34
  • 25
  • 7
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt

  • 93
  • 23
  • 1
Kaninchen

Klonalität

  • 80
  • 37
Polyklonal

Konjugat

  • 87
  • 6
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser KLF4 Antikörper ist unkonjugiert

Applikation

  • 91
  • 55
  • 49
  • 32
  • 29
  • 22
  • 18
  • 10
  • 9
  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 12
    • 9
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    AGCGKTYTKS SHLKAHLRTH TGEKPYHCDW DGCGWKFARS DELTRHYRKH

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against KLF4. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human KLF4
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 470 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Natesampillai, Kerkvliet, Leung, Veldhuis: "Regulation of Kruppel-like factor 4, 9, and 13 genes and the steroidogenic genes LDLR, StAR, and CYP11A in ovarian granulosa cells." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 2, pp. E385-91, (2008) (PubMed).

  • Target

    KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

    Andere Bezeichnung

    KLF4

    Hintergrund

    The mammalian Kruppel-like transcription factor, KLF4 is involved in preventing centrosome amplification following DNA damage caused by gamma-irradiation. It is both necessary and sufficient in preventing centrosome amplification following gamma-radiation-induced DNA damage and does so by transcriptionally suppressing cyclin E expression n. Kruppel-like factor 4 is also known to exhibit checkpoint function during the G1/S and G2/M transitions of the cell cycle.
    Alias Symbols: EZF, GKLF
    Protein Interaction Partner: EP300, CREBBP, SETD7, CTBP1, Dlg4, APP, CUL2, VHL, UBC, TCEB2, SP1, RELA, PRKCD, PPARG, SMARCA4, HDAC2, HDAC7, KAT5, HDAC1, HDAC5, ELK1, KLF6, TP53,
    Protein Size: 470

    Molekulargewicht

    50 kDa

    Gen-ID

    9314

    NCBI Accession

    NM_004235, NP_004226

    UniProt

    O43474

    Pathways

    Peptide Hormone Metabolism, Stem Cell Maintenance
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