TIMELESS Antikörper (N-Term)

Produktnummer ABIN2780561

Der Kaninchen Polyklonal Anti-TIMELESS-Antikörper wurde für WB validiert. Er ist geeignet, TIMELESS in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen, Schaf, Schwein, Kaninchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für TIMELESS Antikörper (N-Term) (ABIN2780561)

Target: TIMELESS (Timeless Homolog (TIMELESS))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen, Schaf, Schwein, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMELESS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TIMELESS Antikörper

Bindungsspezifität: N-Term

Sequenz: MDLHMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TIMELESS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TIMELESS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1208 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TIMELESS

Target: TIMELESS (Timeless Homolog (TIMELESS))

Andere Bezeichnung: TIMELESS

Hintergrund: The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein.
Alias Symbols: TIM, TIM1, hTIM
Protein Interaction Partner: UBC, TUT1, TF, XRCC1, FKBP3, SP1, SUMO2, Tipin, Timeless, ZSCAN1, PCBD1, CRY1, PER2, PER1, CLSPN, PCNA, per, Clock, ATRIP, CRY2, CHEK1,
Protein Size: 1208

Molekulargewicht: 139 kDa

Gen-ID: 8914

NCBI Accession: NM_003920, NP_003911

UniProt: Q9UNS1

Pathways: Protein targeting to Nucleus, Photoperiodism