HMGA1 Antikörper (N-Term)

Produktnummer ABIN2780401

Produktdetails anti-HMGA1 Antikörper

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Pferd, Meerschweinchen, Zebrafisch (Danio rerio), Ziege, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MSESSSKSSQ PLASKQEKDG TEKRGRGRPR KQPPKEPSEV PTPKRPRGRP

Homologie: Cow: 93%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against HMGA1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HMGA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 96 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HMGA1

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Andere Bezeichnung: HMGA1 (HMGA1 Produkte)

Hintergrund: This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: HMG-R, HMGA1A, HMGIY, MGC12816, MGC4242, MGC4854
Protein Interaction Partner: NCOR2, UBE2I, PPARG, UBC, UPF2, HTT, OLA1, DNAJC8, PSIP1, METAP2, SYNCRIP, CWC27, HNRNPDL, EIF2S2, PCBP2, PCBP1, PA2G4, NPM1, NCL, HSPA1A, HNRNPL, HNRNPD, HNRNPAB, HNRNPA1, HMGB3, HMGB2, HMGB1, GTF2F2, XRCC6, CSNK2A1, RCC1, CDK1, APEX1, ANXA2, ANXA1, SSB,
Protein Size: 96

Molekulargewicht: 11 kDa

Gen-ID: 3159

NCBI Accession: NM_002131, NP_002122

UniProt: Q5T6U8

Pathways: Nuclear Hormone Receptor Binding, Autophagie