FOXO3 Antikörper (C-Term)

Produktnummer ABIN2780367

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FOXO3 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Rind (Kuh), Schaf, Pferd, Kaninchen und Meerschweinchen.

Kurzübersicht für FOXO3 Antikörper (C-Term) (ABIN2780367)

Target: FOXO3 (Forkhead Box O3 (FOXO3))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schaf, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXO3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FOXO3 Antikörper

Bindungsspezifität: C-Term

Sequenz: MESIIRSELM DADGLDFNFD SLISTQNVVG LNVGNFTGAK QASSQSWVPG

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FOXO3A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FOXO3A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 453 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FOXO3

Target: FOXO3 (Forkhead Box O3 (FOXO3))

Andere Bezeichnung: FOXO3A

Hintergrund: FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia.
Alias Symbols: FOXO2, AF6q21, FKHRL1, FOXO3A, FKHRL1P2
Protein Interaction Partner: SMAD3, YWHAB, ERBB2IP, SIRT1, YWHAE, CDK6, AKT1, IKBKB, CHUK, CDT1, UBC, SKP2, MAPK1, PCNA, MDM2, BTRC, CREBBP, ELAVL1, SMAD4, MAPK6, NR1H3, NR1H2, NLK, VDR, SMAD1, EP300, STK4, FANCD2, RAD17, MYC, H2AFX, BRCA1, ATM, SIRT3, ATG101, YWHAH, PGK1, GBAS, FKBP
Protein Size: 453

Molekulargewicht: 50 kDa

Gen-ID: 2309

NCBI Accession: NM_001455

UniProt: Q68DV3

Pathways: Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis